Health status and healthcare trends of individuals accessing Australian aged care programmes over a decade: the Registry of Senior Australians historical cohort

BACKGROUND:Understanding the health profile, service, and medicine use of Australians in the aged care sector will help inform appropriate service provision for our ageing population. AIMS:To examine the 2006-2015 trends in (1) co-morbidities and frailty of individuals accessing aged care and (2) health services, medicine use, and mortality after entry into long term care. METHODS:A cross-sectional and population-based trend analysis were conducted using the Registry of Senior Australians. RESULTS:From 2006-2015, 509,944 individuals accessed permanent residential care, 206,394 home care, 283,014 respite, and 124,943 transition care. Over this time, the proportion of individuals accessing permanent residential care with high frailty scores (≥0.3) increased (19.7% to 49.7%), as did the proportion with 5-9 co-morbidities (46.4% to 54.5%), with similar trends observed for those accessing other services. The median number of medicines dispensed in the year after entering permanent residential care increased from 9 (interquartile range (IQR) 6-12) to 10 (IQR 7-14), while remaining stable in home care (2006:9 IQR 5-12, 2015:9, IQR 6-13). Short-term (within 100 days) mortality in those accessing permanent care was higher in 2006 (15.6%, 95%CI 15.2-16.0%) than 2015 (14.6%, 95%CI 14.3-14.9%), while longer term (101-1095 days, 2006: 44.3%, 95%CI 43.7-45.0%, 2015: 46.4%, 95%CI 45.8-46.9%) mortality was higher. Mortality in individuals accessing home care did not change. CONCLUSION:The health of older Australians accessing aged care programs has declined while frailty increased, with an increasing use of medicine and worse long-term mortality in some. Funding and care models need to adapt to this changing profile.Maria C. Inacio, Catherine Lang, Sarah C. E. Bray, Renuka Visvanathan, Craig Whitehead, Elizabeth C. Griffith, Keith Evans, Megan Corlis and Steve Wesseling

Random subcubes as a toy model for constraint satisfaction problems

We present an exactly solvable random-subcube model inspired by the structure of hard constraint satisfaction and optimization problems. Our model reproduces the structure of the solution space of the random k-satisfiability and k-coloring problems, and undergoes the same phase transitions as these problems. The comparison becomes quantitative in the large-k limit. Distance properties, as well the x-satisfiability threshold, are studied. The model is also generalized to define a continuous energy landscape useful for studying several aspects of glassy dynamics.Comment: 21 pages, 4 figure

Abiotic Stress‐Related Expressed Sequence Tags from the Diploid Strawberry Fragaria vesca

Strawberry ( spp.) is a eudicotyledonous plant that belongs to the Rosaceae family, which includes other agronomically important plants such as raspberry ( L.) and several tree-fruit species. Despite the vital role played by cultivated strawberry in agriculture, few stress-related gene expression characterizations of this crop are available. To increase the diversity of available transcriptome sequence, we produced 41,430 L. expressed sequence tags (ESTs) from plants growing under water-, temperature-, and osmotic-stress conditions as well as a combination of heat and osmotic stresses that is often found in irrigated fields. Clustering and assembling of the ESTs resulted in a total of 11,836 contigs and singletons that were annotated using Gene Ontology (GO) terms. Furthermore, over 1200 sequences with no match to available Rosaceae ESTs were found, including six that were assigned the “response to stress” GO category. Analysis of EST frequency provided an estimate of steady state transcript levels, with 91 sequences exhibiting at least a 20-fold difference between treatments. This EST collection represents a useful resource to advance our understanding of the abiotic stress-response mechanisms in strawberry. The sequence information may be translated to valuable tree crops in the Rosaceae family, where whole-plant treatments are not as simple or practical

Learning through 'prosuming': Insights from media literacy programmes in Asia

10.1177/097172180801300205Science, Technology and Society132259-27

Measurement of the neutron magnetic form factor from inclusive quasielastic scattering of polarized electrons from polarized 3He

We report a measurement of the asymmetry in spin-dependent quasielastic scattering of longitudinally polarized electrons from a polarized 3He target. The neutron magnetic form factor GMn has been extracted from the measured asymmetry based on recent PWIA calculations using spin-dependent spectral functions. Our determination of GMn at Q2=0.19 (GeV/c)2 agrees with the dipole parametrization. This experiment represents the first measurement of the neutron magnetic form factor using spin-dependent electron scattering

An Oscillatory Contractile Pole-Force Component Dominates the Traction Forces Exerted by Migrating Amoeboid Cells

We used principal component analysis to dissect the mechanics of chemotaxis of amoeboid cells into a reduced set of dominant components of cellular traction forces and shape changes. The dominant traction force component in wild-type cells accounted for ~40% of the mechanical work performed by these cells, and consisted of the cell attaching at front and back contracting the substrate towards its centroid (pole-force). The time evolution of this pole-force component was responsible for the periodic variations of cell length and strain energy that the cells underwent during migration. We identified four additional canonical components, reproducible from cell to cell, overall accounting for an additional ~20% of mechanical work, and associated with events such as lateral protrusion of pseudopodia. We analyzed mutant strains with contractility defects to quantify the role that non-muscle Myosin II (MyoII) plays in amoeboid motility. In MyoII essential light chain null cells the polar-force component remained dominant. On the other hand, MyoII heavy chain null cells exhibited a different dominant traction force component, with a marked increase in lateral contractile forces, suggesting that cortical contractility and/or enhanced lateral adhesions are important for motility in this cell line. By compressing the mechanics of chemotaxing cells into a reduced set of temporally-resolved degrees of freedom, the present study may contribute to refined models of cell migration that incorporate cell-substrate interactions

Transverse-Longitudinal Asymmetry in the Quasielastic 3He→(e→, e′) Reaction

The transverse-longitudinal asymmetry ATL′ in 3He→(e→, e′) quasielastic scattering at momentum transfer Q2=0.14 (GeV/c)^2 has been measured to be 1.52 ± 0.55(stat) ± 0.15(syst)%. The plane wave impulse approximation (PWIA) prediction for this measurement ranges from 2.1% to 2.9%, where the variation is due to uncertainty in the initial state wave function, nucleon form factors, and off-shell prescription. The data may suggest a suppression with respect to the PWIA, which has also been observed for the unpolarized longitudinal response function

Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study

A41 Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study In: Addiction Science & Clinical Practice 2017, 12(Suppl 1): A4